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62 protocols, every one authored by a named, credentialled physician whose conflicts of interest and full clinical rationale are published. No anonymous stacks.
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Showing 62 of 62
Authored by Dr. Hana Okafor, MSc · For: Adults 25–75, no chronic conditions
The evidence-first floor. Only molecules with multiple well-controlled human trials. What most longevity clinicians take themselves.
The stack
Day cost
$0.94 / day
Authored by Dr. Hana Okafor, MSc · For: Adults 30+ with sub-optimal blood markers
Adds methylation support and a baseline polyphenol on top of the floor protocol.
The stack
Day cost
$1.41 / day
Authored by Dr. Marisol Chen, MD PhD · For: Active adults training ≥4×/week
Foundation tuned for higher protein turnover and recovery. Higher creatine, glutamine, electrolytes.
The stack
Day cost
$1.65 / day
Authored by Dr. Hana Okafor, MSc · For: Adults seeking maximum simplicity
Three products, taken with breakfast. Covers >80% of the foundation benefit at the lowest cost and pill burden.
The stack
Day cost
$0.61 / day
Authored by Dr. Elena Vasquez, MD PhD · For: Adults 40+ targeting cellular energy
Adds NAD+ precursors, mitophagy activator and methyl donor on top of foundation. Dosed per Yoshino, Mills and Amazentis trials.
The stack
Day cost
$2.18 / day
Authored by Dr. Elena Vasquez, MD PhD · For: Adults 30–50 with no symptoms but family history
Half-dose NAD+ precursor + UA every other day. Lower cost, similar biomarker movement at this age.
The stack
Day cost
$1.42 / day
Authored by Dr. Elena Vasquez, MD PhD · For: Adults on statins; cardiometabolic patients
CoQ10 + PQQ to compensate for statin-induced ubiquinone depletion and support biogenesis.
The stack
Day cost
$1.18 / day
Authored by Dr. Marisol Chen, MD PhD · For: Endurance athletes (cycling, running, rowing)
Stacks UA with d-ribose and L-carnitine for sustained mitochondrial throughput at threshold pace.
The stack
Day cost
$2.74 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults with high oxidative stress markers
Targeted antioxidant delivered to the mitochondrial matrix. Pairs with Foundation for systemic baseline.
The stack
Day cost
$2.95 / day
Authored by Dr. Elena Vasquez, MD PhD · For: Adults 55+ with elevated oxidative markers
Glycine + N-acetylcysteine restores glutathione, per Sekhar group's GlyNAC RCT in older adults.
The stack
Day cost
$0.86 / day
Authored by Prof. Marco Lindqvist, PhD · For: Intermittent — two days per month
A short, periodic senolytic pulse. Modelled on Mayo Clinic and Wake Forest fisetin / D+Q trials. Not a daily protocol.
The stack
Day cost
$0.48 / day (avg)
Authored by Prof. Marco Lindqvist, PhD · For: Adults 50+ wanting daily senotherapeutic load
Daily fisetin at maintenance dose. Less intense than the Window, more compliant for older adults.
The stack
Day cost
$0.94 / day
Authored by Dr. Marisol Chen, MD PhD · For: Patients with diagnosed senescence-related condition
Dasatinib + quercetin pulse, 3 consecutive days per cycle. Requires physician oversight.
The stack
Day cost
$1.78 / day (avg)
Authored by Dr. Hana Okafor, MSc · For: Adults preferring food-first senolysis
Whole-food sources of fisetin and quercetin (strawberries, capers, apples) plus a low-dose support stack.
The stack
Day cost
$0.34 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults with elevated CRP
Bioavailable curcumin to suppress SASP-driven inflammation; paired with omega-3 for synergy.
The stack
Day cost
$1.06 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults 35+ wanting cognitive longevity
Creatine + omega-3 + B-complex form the established cognitive floor. Adds choline source for membrane support.
The stack
Day cost
$1.18 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults 50+ with family history of dementia
Aligned with MIND diet evidence: high DHA, lutein, B12, magnesium-l-threonate.
The stack
Day cost
$1.84 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults reporting subjective cognitive complaints
Hericenones from Lion's Mane upregulate NGF; B-complex supports myelin and methylation.
The stack
Day cost
$1.42 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults post-concussion or post-COVID brain fog
DHA + magnesium-L-threonate + low-dose lithium orotate to stabilise neuro-inflammation.
The stack
Day cost
$2.05 / day
Authored by Dr. Hana Okafor, MSc · For: Adults under chronic stress load
L-theanine + ashwagandha + magnesium glycinate; non-sedating, daytime-compatible.
The stack
Day cost
$0.78 / day
Authored by Dr. Hana Okafor, MSc · For: Knowledge workers, students, surgeons
Combines L-theanine with caffeine in 2:1 ratio plus tyrosine to sustain catecholamines.
The stack
Day cost
$0.62 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults with family history of CVD
Omega-3 + K2 + Mg + CoQ10 — the four supplements with the best CVD outcome data.
The stack
Day cost
$1.26 / day
Authored by Dr. Elena Vasquez, MD PhD · For: Adults 50+ with elevated BP
Boosts nitric oxide via two complementary substrates. Backed by a dozen meta-analyses.
The stack
Day cost
$1.05 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults with elevated Lp(a)
Niacin + L-carnitine + Vitamin E (mixed tocotrienols) — modest but consistent Lp(a) reduction.
The stack
Day cost
$1.43 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults post-MI or post-stent
High-dose omega-3 + cocoa flavanols + folate. Per the FLAVIOLA and PURE-omega trials.
The stack
Day cost
$1.84 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults with paroxysmal AFib
High mag glycinate + taurine + low-dose CoQ10. Avoids stimulant ingredients.
The stack
Day cost
$1.12 / day
Authored by Dr. Hana Okafor, MSc · For: Adults with HbA1c 5.7–6.4 (pre-diabetes)
Berberine + alpha-lipoic acid + chromium — the most-replicated insulin-sensitising stack outside of metformin.
The stack
Day cost
$1.32 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults wanting microbiome-driven metabolic improvement
Pasteurised A. muciniphila + cranberry polyphenols — paired with Foundation.
The stack
Day cost
$2.16 / day
Authored by Dr. Hana Okafor, MSc · For: Women with PCOS
Myo-inositol 4 g + d-chiro-inositol 100 mg + berberine — the standard PCOS metabolic stack.
The stack
Day cost
$1.46 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults on semaglutide / tirzepatide
Protects lean mass and bone density during rapid weight loss: creatine, leucine, vitamin K2.
The stack
Day cost
$1.18 / day
Authored by Dr. Elena Vasquez, MD PhD · For: Adults practicing 16:8 TRE
Electrolytes + magnesium glycinate + L-carnitine to support fat oxidation during the fasting window.
The stack
Day cost
$0.92 / day
Authored by Dr. Marisol Chen, MD PhD · For: Women in perimenopause
Magnesium glycinate, omega-3, vitamin D3, plus a standardised black cohosh extract.
The stack
Day cost
$1.04 / day
Authored by Dr. Marisol Chen, MD PhD · For: Men 45+ with declining testosterone
Boron + vitamin D + zinc + ashwagandha — the most-replicated non-prescription stack.
The stack
Day cost
$0.92 / day
Authored by Dr. Hana Okafor, MSc · For: Adults with chronic high cortisol
Phosphatidylserine + ashwagandha + L-theanine — best evidence for blunting evening cortisol.
The stack
Day cost
$1.14 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults with sub-clinical hypothyroidism
Selenium + iodine + zinc — the substrate trio for T4-to-T3 conversion.
The stack
Day cost
$0.62 / day
Authored by Dr. Hana Okafor, MSc · For: Adults wanting baseline immune resilience
Vitamin D3 4000 IU, zinc, and quercetin — the trio with the strongest cold/flu evidence.
The stack
Day cost
$0.74 / day
Authored by Dr. Hana Okafor, MSc · For: First 72 h of an infection
Short-term high-dose stack: zinc lozenges every 2 h, vitamin C, elderberry. Stop after 72 h.
The stack
Day cost
$1.42 / day (avg)
Authored by Prof. Marco Lindqvist, PhD · For: Adults 65+ post-infection
Adds whey protein + leucine on top of the immune floor to support immune cell anabolism.
The stack
Day cost
$1.86 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults 40+ with mild joint discomfort
Collagen peptides (10 g) + vitamin C + glucosamine sulfate. No glucosamine HCl, which fails RCTs.
The stack
Day cost
$0.94 / day
Authored by Dr. Hana Okafor, MSc · For: Athletes with tendinopathy
Hydrolysed collagen (15 g) + vitamin C 30–60 minutes pre-exercise; per Shaw 2017 protocol.
The stack
Day cost
$1.18 / day
Authored by Dr. Marisol Chen, MD PhD · For: Post-menopausal women, BMD T-score < -1
Vit D3 + K2 (MK-4 + MK-7) + boron + magnesium — outperforms calcium alone in trial data.
The stack
Day cost
$1.06 / day
Authored by Dr. Marisol Chen, MD PhD · For: Athletes post-resistance training
Whey + creatine + tart cherry within 30 minutes of training.
The stack
Day cost
$1.34 / day
Authored by Dr. Hana Okafor, MSc · For: Adults with poor sleep architecture
Glycine + magnesium glycinate + apigenin (chamomile flavonoid) — sleep-onset and architecture support.
The stack
Day cost
$0.62 / day
Authored by Dr. Hana Okafor, MSc · For: Occasional alcohol consumption
DHM + NAC + B1 to scavenge acetaldehyde and protect glutathione.
The stack
Day cost
$1.04 / day (event)
Authored by Dr. Marisol Chen, MD PhD · For: Women planning pregnancy
Methylated folate (5-MTHF) 800 µg, choline 450 mg, omega-3 (high DHA), vitamin D3.
The stack
Day cost
$1.12 / day
Authored by Dr. Marisol Chen, MD PhD · For: First 12 months post-partum
Iron bisglycinate, B12, DHA, vitamin D, magnesium glycinate — addresses common deficits.
The stack
Day cost
$1.32 / day
Authored by Dr. Marisol Chen, MD PhD · For: Women in early menopause
Combined bone density + cognitive support stack tuned for menopause.
The stack
Day cost
$1.74 / day
Authored by Dr. Marisol Chen, MD PhD · For: Men 50+ with mild BPH
Saw palmetto + zinc + lycopene — the consensus first-line nutritional stack.
The stack
Day cost
$0.92 / day
Authored by Prof. Marco Lindqvist, PhD · For: Couples planning conception
L-carnitine + CoQ10 + zinc + selenium — the strongest meta-analytic support for sperm parameters.
The stack
Day cost
$1.46 / day
Authored by Dr. Hana Okafor, MSc · For: Adults concerned about skin AGEs
Carnosine + alpha-lipoic acid + vitamin C — three molecules with skin AGE reduction trials.
The stack
Day cost
$1.21 / day
Authored by Dr. Hana Okafor, MSc · For: Adults wanting skin elasticity support
Hydrolysed collagen 10 g + vitamin C + biotin + silica.
The stack
Day cost
$0.94 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults with early androgenic alopecia
Saw palmetto + biotin + zinc + iron (if ferritin <70).
The stack
Day cost
$0.78 / day
Authored by Dr. Hana Okafor, MSc · For: Adults with mild sleep onset latency
Mag glycinate + glycine + L-theanine — non-habituating, daytime-safe.
The stack
Day cost
$0.52 / day
Authored by Prof. Marco Lindqvist, PhD · For: Night-shift and rotating-shift workers
Low-dose melatonin (0.3 mg) + apigenin + glycine — circadian re-anchor without grogginess.
The stack
Day cost
$0.68 / day
Authored by Dr. Hana Okafor, MSc · For: Frequent transmeridian travellers
Melatonin 0.5 mg at destination bedtime + bright light exposure protocol; magnesium for muscle calm.
The stack
Day cost
$0.42 / day (event)
Authored by Prof. Marco Lindqvist, PhD · For: Self-experimenters, weekly biomarker monitoring · Inspired by David Sinclair
Reproduces Sinclair's published self-experiment with TMG, NMN, resveratrol, metformin (Rx) and statin (Rx).
The stack
Day cost
$3.84 / day
Authored by Dr. Marisol Chen, MD PhD · For: High-resource patients with full lipidology · Inspired by Peter Attia
Foundation + EPA + Lp(a) management stack + rapamycin (Rx, weekly).
The stack
Day cost
$4.12 / day
Authored by Prof. Marco Lindqvist, PhD · For: Self-experimenters tracking 100+ biomarkers · Inspired by Bryan Johnson
Heavily-stacked Foundation with NAD+, autophagy, cardiovascular, cognitive, mitochondrial layers.
The stack
Day cost
$5.84 / day
Authored by Dr. Marisol Chen, MD PhD · For: Adults under physician supervision
Per the Mannick / Kaeberlein protocol: rapamycin 5–8 mg once weekly, with metabolic monitoring.
The stack
Day cost
$2.41 / day (avg)
Authored by Prof. Marco Lindqvist, PhD · For: Patients in clinical trials of reprogramming therapeutics
Methyl donors + folate + B12 + Vit C — substrate support during epigenetic perturbation.
The stack
Day cost
$0.94 / day
Authored by Dr. Marisol Chen, MD PhD · For: Patients undergoing HBOT for healthspan
Antioxidants timed around HBOT sessions to capture hormesis without oxidative overshoot.
The stack
Day cost
$1.42 / day
Authored by Prof. Marco Lindqvist, PhD · For: Adults seeking vascular & renal aging support
Vitamin D, vitamin K2, magnesium and exercise are the only validated klotho-supportive levers.
The stack
Day cost
$0.96 / day
All protocols are based on peer-reviewed human trials and independently verified. Dosages are optimized for safety and efficacy.
For personalized recommendations, consult with a healthcare provider. These protocols are for educational purposes only.