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Frontier · Expert StackUpdated April 2026

Morgan Levine

Principal Investigator, Altos Labs · Former Yale Professor · Author, True Age

Levine developed PhenoAge and GrimAge — two of the most validated biological age clocks. Her work shows that biological age is modifiable and that lifestyle interventions can measurably reverse it. She advocates for measuring, not guessing, your rate of aging.

Supplement Stack

Rapamycin
5 mg / week
II
Timing:Once weekly
Nutrient-sensing dysreg.Cellular senescence
Prescription only. Levine uses low-dose weekly rapamycin.
Rx only — not added to cart
Metformin
500 mg
I
Timing:Evening
Nutrient-sensing dysreg.Cellular senescence
Prescription only.
Rx only — not added to cart
Omega-3
1 g
I
Timing:With meal
Microbiome alterationsDisabled autophagy
Vitamin D3
2000 IU
I
Timing:Morning
Disabled autophagy

Tier I = multiple RCTs in humans · Tier II = human trials, early stage · Tier III = mechanism / animal studies only

Lifestyle Pillars

  • 1Tracks biological age quarterly using epigenetic clock tests
  • 2Mediterranean-style diet with emphasis on whole foods
  • 3Regular aerobic exercise — running and cycling
  • 4Prioritises sleep quality and consistency
  • 5Stress management through mindfulness and social connection

Important Caveats

Levine's supplement protocol is intentionally conservative — she emphasises that lifestyle factors (diet, exercise, sleep) account for the majority of biological age variance. Her primary contribution is measurement methodology, not supplement optimisation.

Sources & References

Add to cart

4 of 4 molecules are available in the index.

2 Rx-only items excluded — requires physician prescription.
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Compare stacks

See how Morgan's stack compares to Attia, Sinclair, Patrick, Huberman, and Johnson side-by-side.

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Stack summary

Total molecules4
Tier I (RCT)3
Tier II (human trials)1
Tier III (mechanism)0
Rx-only items2
In your cart0
This protocol is curated by Vitaei from publicly available information. It is not endorsed by Morgan Levine and does not constitute medical advice. Consult a physician before starting any supplement or medication regimen.